Welcome to the Laboratory of Cardiovascular Biochemistry
My lab uses the tools of protein biochemistry & proteomics to tackle fundamental problems in cardiac preconditioning, cardiomyopathy and heart failure. Specific projects include:
- using proteomics to discover the molecular Identity of the long-sought cardioprotective mitochondrial KATP channel (see more).
- defining the proteome of the heart…in fruit flies. By combining proteomics with the power of Drosophila genetics we can obtain a fingerprint of cardiac maladaptive remodeling in hypertrophic and dilated cardiomyopathy. Identifying evolutionarily conserved pathways may point the way to novel therapeutic strategies (see more).
- mapping changes in post translational modification networks that accompany the progression of heart failure (see more).
D. Brian Foster Ph.D.
Assistant Professor of Medicine, Division of Cardiology
Director, Laboratory of Cardiovascular Biochemistry
The Johns Hopkins University School of Medicine
Ross Research Building
720 Rutland Avenue Baltimore, MD 21205