Lab Funding

R01HL134821

(PI: O’Rourke (Contact), Foster)

04/01/2018-02/28/2022

NIH/NHLBI
Role: Principal Inv.
Targeting Metabo-Redox Network Vulnerability in Heart Failure and Sudden Death
This project takes a systems approach to map ROS-sensitive pathways in HF progression.

AHA

AHA Transformational Project Award

PI: Foster

07/01/18-06/30/21

18TPA34170575 Preserving Cardiac Retinoic Acid Homeostasis as a Therapeutic Approach to Heart Failure. This goal of this grant is to characterize the factors that dictated levels of ATRA in Heart and how they are perturbed in the context of heart failure.

Johns Hopkins

Magic That Matters Award

PI: Foster

01/01/18-06/31/19

Div. of Cardiology Modulation of Cardiac all-trans Retinoic Acid Metabolism to Prevent Heart Failure.
This award provides pilot funding for the development of CYP26 knockout mouse models to modulate levels of cardiac ATRA and determine its impact on TAC-induced hypertrophy.

Johns Hopkins

Catalyst Award

PI: Foster

07/01/17-06/30/18

Office of the Provost The Role of Retinoic Acid Deficiency in the Pathogenesis of Heart Failure and Sudden Cardiac Death. This award provides pilot funding for the development of CYP26 knockout mouse models to modulate levels of cardiac ATRA and determine its impact on TAC-induced hypertrophy.

Completed or Declined

R21HL108052

(PI: Foster, Co-PI: O’Rourke)

08/27/12-08/26/14

NIH/NHLBI
Role: Principal Inv.
A Systems Biology Approach to Cardiomyopathy in a D. melanogaster Model
The primary goal is to map the retrograde signaling from cardiomyopathy mutations using a quantitative proteomic approach

12SDG12060056

AHA National Scientist Development Grant (PI: Foster)

07/01/12-06/30/16

AHA/Nat. Center
Role: Principle Inv.
Characterizing MitoROMK, the K+ channel subunit of MitoKATP
This project aims to capitalize on the discovery of MitoROMK, to find and validate both binding partners and post-translational modifications of the pore-forming and regulatory subunits of MitoKATP.

12BGIA11880002

Beginning Grant-in-Aid (PI: Foster)

Awarded and Declined, June 2012

AHA/Mid-Atlantic
Role: Principal Inv.
A Systems Biology Approach to Cardiomyopathy using D. melanogaster as a Model System
The primary goal is to map the retrograde signaling from cardiomyopathy mutations using a quantitative proteomic approach. It was declined to accept 12SDG12060056. The project was subsequently funded under R21HL108052

0120299T

AHA Postdoctoral Fellowship (PI: Foster)

07/01/01-06/30/03

AHA/Founders Affil.
Role: Principal Inv.
Structural Investigation of Muscle Thin Filaments Using 3D Helical Image Reconstruction of Electron Micrographs